double-stranded break

double-stranded break
двухнитевой разрыв; двухцепочечный разрыв

English-Russian small dictionary of medicine. . 2015.

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  • break — Separation into parts. double strand b. a b. in double stranded DNA in which both strands have been cleaved; however, the two strands have not separated from each other. single strand b. a b. in double stranded DNA in which only one of the two… …   Medical dictionary

  • DNA — For a non technical introduction to the topic, see Introduction to genetics. For other uses, see DNA (disambiguation). The structure of the DNA double helix. The atoms in the structure are colour coded by element and the detailed structure of two …   Wikipedia

  • Chromosomal crossover — Thomas Hunt Morgan s illustration of crossing over (1916) A double cros …   Wikipedia

  • Type II topoisomerase — Type II topoisomerases cut both strands of the DNA helix simultaneously in order to change the linking number of the molecule. FunctionOnce cut, the ends of the DNA are separated, and a second DNA duplex is passed through the break. Following… …   Wikipedia

  • Delitto perfetto — is a genetic technique for in vivo site directed mutagenesis in yeast. This name is an Italian term for perfect deletion and is also an idiom for perfect murder. The name refers to the ability of the technique to create desired genetic changes… …   Wikipedia

  • Spo11 — is a protein used in a complex along with Mre11 and Rad50 during meiotic recombination. It is also involved in the creation of double stranded breaks in the DNA in the early stages of this process. Its active site contains a tyrosine which… …   Wikipedia

  • Cre-Lox recombination — is a special type of site specific recombination developed by Dr. Brian Sauer initially for use in activating gene expression in mammalian cell lines and transgenic mice (DuPont).[1][2] Subsequently, the laboratory of Dr. Jamey Marth showed that… …   Wikipedia

  • Recombination activating gene — protein Name=recombination activating gene 1 caption= width= HGNCid=9831 Symbol=RAG1 AltSymbols= EntrezGene=5896 OMIM=179615 RefSeq=NM 000448 UniProt=P15918 PDB= ECnumber= Chromosome=11 Arm=p Band=13 LocusSupplementaryData=protein… …   Wikipedia

  • ATM (Gene) — Protéine ATM Pour les articles homonymes, voir ATM. La protéine ATM, en anglais Ataxia telangiectasia mutated, est la protéine mutée dans le syndrome d ataxie télangiectasie. Elle répare les cassures double brins dans l’ADN occasionnés par des… …   Wikipédia en Français

  • ATM (Gène) — Protéine ATM Pour les articles homonymes, voir ATM. La protéine ATM, en anglais Ataxia telangiectasia mutated, est la protéine mutée dans le syndrome d ataxie télangiectasie. Elle répare les cassures double brins dans l’ADN occasionnés par des… …   Wikipédia en Français

  • Proteine ATM — Protéine ATM Pour les articles homonymes, voir ATM. La protéine ATM, en anglais Ataxia telangiectasia mutated, est la protéine mutée dans le syndrome d ataxie télangiectasie. Elle répare les cassures double brins dans l’ADN occasionnés par des… …   Wikipédia en Français


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